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Engin Serpersu

Contact Info

FacultySerpersuEngin Serpersu
Professor Emeritus

Office : WLS, F331: 865-974-2668

Lab: WLS, D-413, -417: (865-974-4075, -2530)

Email: Serpersu@utk.edu

Website:  serpersulab.utk.edu

Ph.D. Medical School, Hacettepe University (Turkey)

 

Selected Publications

Norris, A.L., Nickels, J. Sokolov, A. P., and Serpersu, E. H. (2014) Protein dynamics are influenced by the order of ligand binding to an antibiotic resistance enzyme. Biochemistry 53,30-38.

Norris, A. L. and Serpersu, E. H. (2013) Ligand promiscuity through the eyes of the Aminoglycoside N3 Acetyltransferase IIa. Prot. Sci. 22, 916-928.

Jing, X., Wright, E., Bible, A. N., Peterson, C. B., Alexandre, G., Bruce, B. D. and Serpersu, E. H.. (2012) Thermodynamic Characterization of a Thermostable Antibiotic Resistance Enzyme, the Aminoglycoside Nucleotidyltransferase (4ʹ). Biochemistry 51, 9147-9155.

Serpersu, E. H. and Norris, A. L. (2012) Effect of protein dynamics and solvent in ligand recognition by promiscuous aminoglycoside-modifying enzymes. Adv. Carbohydr. Chem. Biochem. (Horton, D. ed.) Elsevier, 67, 221-248.

Norris, A. L. and Serpersu, E. H. (2011) Antibiotic Selection by the Promiscuous Aminoglycoside Acetyltransferase-(3)-IIIb is Thermodynamically Achieved Through Control of Solvent Rearrangement. Biochemistry 50,9309-9317.

Norris, A. L. and Serpersu, E. H. (2009) NMR Detected Hydrogen-Deuterium Exchange Reveals Differential Dynamics of Antibiotic and Nucleotide Bound Aminoglycoside Phosphotransferase 3′-IIIa. J. Am. Chem. Soc. 131,8487-8594.

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