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Drs. Baudry and Smith publish in Science Signaling

Drs. Jerome Baudry and Jeremy Smith published an article in Science Signaling entitled: A computationally identified compound antagonizes excess FGF-23 signBaudry_Jerome2aling in renal tubules and a mouse model of hypophosphatemia. This collaboration between researchers at UT-Knoxville, ORNL, Earlham College, Tennessee Technology University and UT-Memphis used computational approaches to identify compounds to bind fibroblast growth factor-23 rather than the receptors. Experiments confirmed that this may be aSmith_Jeremy new therapeutic approach for drug design. Click here to access the article online.