At the recent annual meeting in Philadelphia of ASBMB (American Society for Biochemistry and Molecular Biology), Fran Barrera co-organized with Matthias Buck (Case Western Reserve University) for the second year in a row a session consisting of a Protein Interest Group, on the topic of Membrane proteins. Interest groups bring together a diverse audience. The session was well attended, with a packed room, who came to see four talks (including Fran’s), and was capped by an animated discussion between the speakers and the audience on the challenges and future directions of the field. More information about the interest groups from this year’s meeting can be found here. Consider attending the 2023 meeting in Seattle.