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Lamichhane Lab Publishes in JBC

Recent studies from the Lamichhane Lab (https:/ have revealed the dynamics of the extracellular domain (ECD) of the glucagon receptor (GCGR). The work published in the Journal of Biological Chemistry (JBC) employed single-molecule molecule fluorescence microscopy to demonstrate that the glucagon-bound ECD of the GCGR is dynamic, which was not explored previously. Glucagon is a hormone produced by the pancreas and plays a key role in regulating blood glucose levels, and the GCGR is an important target for treating type 2 diabetes. The first author of the publication is Dr. Ting Liu (former postdoc), and co-authors include a graduate student (Susmiat Khanal) and an undergraduate student Gillian Hertslet.